Chapter 654
Chapter 627 Active compound
After a day and night of fierce battle, cheers rang out in the laboratory: “It’s done!”
A new compound is born, and the next steps are various tests.
The chemical structure test data shows that this is an eight-membered heterocyclic compound.
“Director Shen, give this eight-membered heterocyclic compound a name.” Cao Fan, who has grown up, said excitedly and expectantly.
Naming new compounds is a basic operation. Anyone in this laboratory can be proficient in using more than three international naming rules.
Some time ago, He Lin and Cao Fan made seven-membered heterocyclic compounds.
They use compounds a, b, c…z to note these seven-membered heterocyclic compounds. If the English letters are used up, they will continue to use the combination of English letters + Arabic numerals.
In this project, compounds below eight yuan do not deserve to have official chemical names, because they are all process products.
Of course, the products of these processes are also meaningful. Without a process, where would the result come from?
This new eight-membered heterocyclic compound is different, it is to be tested for activity. If the activity test passes, the next step is to synthesize a drug.
The finished medicine came out and passed several clinical phases, then the project was a success.
If the LPJK1 project is successful, it is not only a victory for drug synthesis, but also a victory for basic theoretical research.
The comprehensive victory of academic research combined with engineering application, the result of the victory is to save one’s life and build a seventh-level Buddha.
At such a meaningful moment, the public unanimously suggested that Shen Qi should handle the naming of the first eight-membered heterocyclic compound.
“Then I would be more respectful than fate.” Shen Qi folded his hands together to express his gratitude, and he thanked everyone for their efforts.
There are several naming principles for heterocyclic compounds in the world, and Shen Qi decided to adopt the Hanqi-Weidmann heterocyclic system nomenclature.
In this naming system, the suffix of the unsaturated ring with the largest number of non-cumulative double bonds is generally adopted. The three- to ten-membered ring corresponds to Tiangan’s methyl, ethyl, propyl, butyl, hexamethylene, hexyl, and hexyl, and eleven, twelve… …
Based on the Hanqi-Weidman heterocyclic ring system nomenclature, Shen Qi quickly gave the name: “1,3,4-triazaoctane ring, thanks for your hard work, let’s do an activity test.”
The daily life of a chemical dog is one experiment after another, and one test after another.
Patriotic, dedicated, honest and friendly.
Since you have chosen this career, let’s do it forever.
Activity test is to select specific cells and process them into test cell lines, and then perform specific activity tests on the synthesized compounds.
The activity test result is OK, then the active compound can enter the animal experiment stage.
If it is not OK, then the aforementioned “saving a life is better than building a seven-level float” is equivalent to blowing water.
“The activity test of compound 1,3,4-triazaoctane ring is in progress.
The experimenters cheered up and did the test.
“OK! The activity test is OK!”
Good news, the LPJK1 project finally has an active compound.
But one active compound is far from enough. What if it doesn’t pass animal experiments?
So you need to reserve a few more active compounds.
For a drug project, small pharmaceutical companies outside usually prepare two or three active compounds, and large pharmaceutical companies generally stock more than 20. A pharmaceutical giant like GLK often prepares 60 or 70 active compounds.
The active compounds that have passed animal experiments have value in the market. If it passes the first clinical phase, its value will continue to increase.
Most small pharmaceutical companies do not make new drugs. They sell the active compounds to large pharmaceutical companies after they have obtained the active compounds, passed animal experiments or the first phase of clinical trials.
The second and third clinical phases are too costly, and small pharmaceutical companies simply can’t afford it.
The patent development right of LPJK1 has been sold to OBB Pharmaceuticals. The model of OBB Pharmaceuticals is the cooperation of factories with laboratories.
Shen Qi’s laboratory gave Obeqi Pharmaceutical what it was, and Obeqi Pharmaceutical did what it did.
“Continue to make active compounds, and make 1,3,4-triazaoctane derivatives.” Shen Qi leads everyone to continue their efforts, accumulate grain and make more active compounds.
on Monday.
The Chemistry Laboratory of the Shen Qi Research Center reported a good news again: “It was a success. The 1,3,4-triazaoctane derivative 1 was synthesized!”
“OK, OK! The activity test result of 1,3,4-triazaoctane derivative 1 is very OK!”
on Tuesday.
The chemistry laboratory of the Shen Qi Scientific Research Center was excited: “It’s done, it’s done, and the 1,3,4-triazaoctane derivative 2 has been synthesized!”
“No problem, no problem! The activity test result of 1,3,4-triazaoctane derivative 2 is no problem!”
on Wednesday.
“Damn, fail, fail!”
Thursday.
“Awesome! The third derivative activity test is excellent!”
Friday is the same as Thursday, so omitted.
Work overtime on Saturday, the result is similar to Wednesday, but failed.
Continue to work overtime on Sunday, and the result is as good as Friday, so omitted.
Including 1,3,4-triazaoctane ring, in one week, the Chemistry Laboratory of Shen Qi Research Center made 6 active compounds that passed the activity test.
In other words, Shen Qi and the group make an active compound a day on average.
This efficiency is terrible.
The horror continues.
Under the leadership of an award-winning and leading mathematician and physicist, the Chemistry Laboratory of the Shen Qi Research Center produced 22 active compounds in one month.
Compared with the laboratories of large pharmaceutical companies, the efficiency and success rate of Shen Qi’s laboratory are several times that of them.
The LPJK1 project has advanced to the current stage, and the degree of confidentiality is very high.
In this sensitive period, Miss Lucy Walker from GLK visited Shen Qi on the grounds of academic exchanges.
Shen Qi got to know Lucy because of the last time the British academic delegation visited China The British academic delegation had already returned to Britain. Miss Lucy stayed in China. Her current identity is the head of GLK China. The person in charge of the company’s business.
To briefly mention, the last time the British academic delegation visited China was very successful. The Chinese and British sides reached a high degree of consensus on many academic research projects and engineering application projects, and specific cooperation in different fields will be carried out in the future.
Shen Qi received the British delegation with a very friendly and very professional professionalism, which was highly praised and deeply recognized by the British side. The British expressed sincere gratitude to the Chinese Foreign Affairs Agency and sincerely hope that the Chinese academic delegation will be able to do so in the near future. Visit Britain.
In view of Shen Qi’s outstanding performance in the field of diplomacy, the state has plans to arrange for Shen Qi to continue to receive the French academic delegation, the Swedish academic delegation and the Japanese academic delegation.
Shen Qi received Miss Lucy who came to visit at the central cafe. He looked at his watch and said, “Lucy, I only have ten minutes. You can pick the key points.”
Lucy made a helpless and dissatisfied expression, and said to her, Professor Shen that you have changed.