NOVEL WEB Chapter 687
Chapter 660 Bells and whistles
“Qi, when you come to the hospital, bring me something.” Ou Ye called Shen Qi.
Shen Qi said in his office while looking up the literature: “Okay, what should I bring?”
Ou Ye: “Book 15 of Gauss’ Notes.”
“Huh? You want to read this volume of Gauss Notes?” Shen Qi was a little surprised. The document in his hand was Volume 15 of Phillips Klein’s Gauss Notes.
There are 20 volumes of Gauss’s handwritten notes in German, all of which are kept in academic institutions in Germany and are not for sale. Even the head of Gauss was printed on the Deutsche Mark circulated in 1989 and 2001. It can be seen that the Germans have great respect for scientists, and the heads of kings, queens or presidents are often printed on the currencies of other countries.
Gauss is the founder of the Göttingen School, and Phillips Klein is the descendant of the Gauss Göttingen School.
This Phillips Klein is exactly the Klein driven crazy by his good friend Poincaré.
After going crazy, Phillips Klein lost his fighting power in solving mathematical problems. In his later years, he focused on writing the history of mathematics and translated Gauss’s 20 volumes of notes into English, French, Latin and other languages.
Phillips Klein’s hand-written translation of the English version of the Gaussian notes went through several rounds and was eventually collected by the Princeton Institute for Advanced Study.
When Shen Qi returned from the United States, he brought back 1518 copies of Phillips Klein’s English version of Gauss’s notes.
The Germans will not hand over the original Gaussian notes in any form, and the Klein version of the Gaussian notes has become an antique artifact today.
In fact, the Gauss Notes have been published long ago, translated into various languages by the publishing group and sold globally.
However, mathematicians with status, status, spare money, and feelings are more willing to collect manuscripts.
Shen Qi’s own manuscripts were either given away or exchanged with other collectors.
Klein’s English version of Gauss’s Notes 1518, was replaced by Shen Qi.
The manuscripts and cultural relics more than a hundred years ago should not be read frequently, otherwise they would be easily damaged.
It was at the critical sprint moment that Shen Qi took out the manuscripts of scientists in history for review.
He and his wife, as well as many top mathematicians, believe that there is not only a compelling difference between manuscripts and printed materials, but also a spiritual imprint that has not yet been confirmed but vaguely exists.
“Ok, I will bring you the Gauss Notes later, what else do I need?”
“Auntie’s towel.”
“Okay, wait for me, see you in twenty minutes.”
Ou Ye’s needs are extremely simple, academic and physiological.
According to the request, Shen Qi took the Gauss note and aunt’s towel to Ou Ye’s ward.
“So wife, do you plan to cut from the Gaussian quadratic domain into rank greater than or equal to 2?”
“Well, I think it’s feasible. Odd, what do you think?”
“I think it’s feasible, so let’s do it.”
Shen Qi suddenly felt very complicated.
Ou Ye couldn’t find inspiration for mathematics at home, and even fainted.
Once hospitalized, Ou Ye seemed to enter a higher academic realm.
Not long after Shen Qigang left the hospital, some new reports came out from the international chemistry community.
The research team at the University of California, Berkeley said that they have successfully synthesized a macrocyclic compound with 20 chiral centers in the laboratory, and the number of isomers is 2 to the 20th power.
“So fierce?”
This was Shen Qi’s first reaction after seeing this report.
The Berkeley research team pointed out in the report: “We have referenced the research results of macrocyclic compounds by the Yanda Shenqi team and synthesized the macrocyclic compounds with the most chiral centers so far. The use of this macrocyclic compound needs further research. But we have made historic progress in the structure of new compounds.”
The University of Tokyo research team said that they synthesized a new type of macrocyclic compound with an extremely complex structure in the laboratory. This new compound is similar to the chemical structure of anemone toxin, except that the key parts are macrocyclic structures with more than eight yuan.
The University of Tokyo research team also thanked Shen Qi’s team for providing the theory of macrocyclic compounds a few months ago. They called the new compound “lighthouse jellyfish hormone”. They called this new compound, which helped reveal some mysteries in nature. The problem.
Research teams in Germany, the United Kingdom, and Australia also reported their latest research progress on macrocyclic compounds. They proved through experiments that the theory of macrocyclic compounds and new rearrangement reactions proposed by Shen Qi’s team is very reliable. .
“This…this is a bit out of control.”
Shen Qi didn’t know whether he should be happy or worried.
He proposed the theory of macrocyclic compounds. After the introduction of this set of theories, various new and fancy products were derived from chemists in various countries.
At present, it is difficult to judge the actual impact that the bells and whistles may bring.
Shen Qi’s intuition told him that the emergence of a large number of new macrocyclic compounds is a double-edged sword, which can be used to benefit mankind, but to destroy the world.
System: “The host has completed the task of chemistry promotion to level 14, upgrade!
Requirements for promotion to level 15 in chemistry:
1. 60 million Xueba points
2. Use chemical means to reveal a kind of mystery. ”
In any case, chemistry is promoted to level 14, it is always worthy of joy.
Mathematics and physics are promoted to 14 grades, which are all directed.
The system requires Shen Qi to solve some specific mathematics and physics problems before Shen Qi can be promoted to level 15.
The condition 2 for chemistry promotion to level 15 is open, and Shen Qi needs to explore it by himself.
Yanda People’s Hospital.
The tolerable administration of triazaoctene was completed.
A team of research physicians headed by Professor Qu, uses statistical methods to process clinical data such as the number of individuals, mean, median, standard deviation, coefficient of variation, geometric mean, geometric standard deviation, etc. Combined with clinical observation And data analysis, Professor Qu’s team believes that triazaoctene passed the tolerance test, and all the subjects will enter the pharmacodynamic test link.
Many literatures reported that the success rate of a new drug in the clinical research phase is about 10, that is, only one of the 10 drug candidates can finally be marketed.
Studies have shown that the main reasons for the failure of clinical development are effectiveness and safety.
It is the most basic requirement for a drug to have good safety and no serious side effects if it can not be eaten.
The core indicator that determines whether a new drug can be marketed is effectiveness, that is, the effectiveness of the drug in treating patients.
In order to avoid the failure of expensive drugs in Phase III clinical trials, in Phase I and II clinical trials, it is necessary to carry out proof-of-concept with effectiveness as an indicator, so that drugs that are not easy to develop successfully will be eliminated as soon as possible, so as not to waste money. .
Based on the above clinical trial ideas, Ou Ye finally took triazaoctene again. (https://)