Chapter 677
Chapter 650 I like eating best
The phone dialed.
“Mom, this is Nophie.”
“Well, Nophie is so good.”
“Mom, how are you in the hospital?”
“Don’t worry, baby Nophie, mom is fine.”
“Mom, is the hospital signal okay?”
“It’s good, I…”
Shen Qi suddenly interrupted: “My child, mother, just focus on the point, Professor Qu will go to your place soon.”
“Oh, okay, Nophie, mom is doing a routine checkup, there is nothing wrong with it. You have to listen to your dad at home, you know?”
“Hmm!”
“Nofi, let dad take you to buy a new red dress, red shoes, red hair card, and then you put it on, ask dad to take pictures and send it to mom, okay?”
“OK.”
“My baby is awesome! Mom loves you.”
“Nofi loves her mother, too.”
“Mua ”
“Mua ”
“Nofi, goodbye.”
“Bye bye mom.”
The mother and daughter ended the call, and Shen Qi said to Nuofi, “Is your mother okay, she is fine.”
“Well, I hope my mother will go home soon.” Shen Nuofei felt a little relieved. During the call just now, she felt that her mother seemed to be quite normal.
The hungry voice sounded.
Nofi patted her belly and said, “Eh, I’m so hungry.”
Shen Qi touched her daughter’s head: “Do you want to finish lunch in the kindergarten, or do you want to go out with your dad?”
Nofinunu mouth: “Children do multiple choice questions.”
“Could it be that you, a big boy, want to have two lunches in a row?”
“I like eating the most.”
“Go, go, eat!”
The daughter is the lover of his father’s last life, so he still needs to coax her to eat.
Yan Great People’s Hospital.
The actual situation of Ou Yeh is not as good as she showed on the phone.
After taking triazaoctene for two weeks, Ou Ye has experienced reactions such as loss of appetite and lethargy.
These are all normal clinical drug reactions, and Ou Ye forced himself to persevere.
Before being admitted to the hospital, Ou Ye ate very little for three meals a day.
was admitted to the hospital for clinical trials, and I ate less Ou Ye.
One person eats less, so his complexion and mental outlook are of course not much better.
Ou Ye is about 1.6 meters tall and close to 1.7 meters tall, and now she weighs only more than 70 catties.
And Shen Nuofei, the little loli who is less than 1.2 meters, weighs more than fifty catties.
You can imagine how thin Ou Ye is.
She didn’t want her daughter to see her face turned pale.
Whether it is a mother or a father, I always want to show my child the most handsome, most beautiful, most energetic, and most proud of myself.
Ou Ye turned on the camera function of the phone, and the camera pointed at her face.
The face of Ou Ye on the screen is yellowish and thin. She is most proud of the one-meter-long black straight black silk, but it is withered and dull.
“I’m so ugly…” Ou Ye murmured. She really couldn’t stand it anymore, so she turned off the camera.
A woman has lost her beauty, her vitality, and her health.
Will her husband remain loyal to this marriage?
To make a more vulgar assumption, a frail and sickly woman who hasn’t done anything between husband and wife with her energetic, tiger-wolf-year-old husband for a long time, will the husband cheat physically or mentally?
Maybe, it will…
It is said that there is no filial son before the bed for a long time.
Is there a loyal husband in front of the bed for so long?
Maybe, yes…
The ellipsis represents uncertainty.
Ou Ye is not sure, she can only think about the good side.
medicine.
Take medicine.
I must get better as soon as possible.
For the children, for the husband, for the family, and for myself.
medicine.
Take more medicine.
Vigorously miracle.
However, medicines should not be taken indiscriminately, and not too much.
In the phase I clinical trial, the tolerance test has strict dosage standards.
The lowest dose is usually calculated from the NOAEL of the most suitable animal, and then divided by the safety factor to obtain the human MD.
Set up several groups from the minimum initial dose to the maximum dose, at least 5 dose groups including the lowest, lower, medium, higher, and highest dose groups. Each subject is only allowed to receive one dose of the test.
Ou Ye was arranged to enter the lowest-dose test group, which was fully considered by the research physician and Shen Qi.
Three-drug. The more medicine you take and the larger the dose, the stronger the toxicological effects.
Phase I clinical is mainly to test the safety of new drugs and the dose that the subjects can bear.
Regardless of whether you eat more or less, there are usually adverse reactions.
Once severe adverse reactions such as death, life-threatening, organ failure, disability, and deformity occur, new drugs will be knocked off.
Loss of appetite, vomiting, and lethargy were considered acceptable adverse reactions by the research physician team in this clinical trial.
Ou Ye had an acceptable adverse reaction, uncomfortable is a bit uncomfortable, but it is also normal.
At this time, the door of the ward opened, and the doctor in charge, Professor Qu, walked in.
Ou Ye, lying on the bed, struggled to get up. Professor Qu hurriedly stopped: “Professor Ou, you can just lie down.”
After that, Professor Qu adjusted the inclination angle of the backrest of the hospital bed so that Ou Ye could communicate with him in as comfortable a posture as possible.
“Excuse me, Professor Qu.” Ou Ye managed to squeeze a smile, which looked almost like no smile.
“No trouble, no trouble, you are a patient, I am a doctor, and I should serve you. What’s more, Professor Shen is my friend, you are also my friend, and it’s okay to serve my friends.” Professor Qu drew his hands. Said: “You have been taking the medicine for two weeks, and no serious adverse reactions have been found. The core indicators of hemoglobin concentration, hematocrit, protein saturation, and CRP are all normal In other words, you It seems safe to take this new drug at this dose.”
“Professor Ou, you are in the lowest-dose group. The lowest-dose group is the first to undergo a tolerance test. After a week, your lowest-dose group’s tolerance test will be completed. If the lowest-dose group is verified to be still safe at that time, Then Professor Ou can go home to recuperate first, and you will come back to our hospital when you do pharmacokinetics/pharmaceutical efficacy tests later. In fact, it’s not a big deal. As your research physician and your friend, I’m here to chat with you. See if you have any needs?”
Professor Qu communicated with Ou Ye in a more relaxed tone, which improved Ou Ye’s sense of security.
“Professor Qu, can I increase the dose when I do the pharmacokinetic/pharmacodynamic test?” Ou Ye put forward her request.
Professor Qu shook his head and said: “We can’t, we can’t do this. We must strictly abide by the clinical trial standards, first for the benefit of patients, and second for better scientific research. Ou, I understand your desire for recovery. Urgent, but I’ll tell you again. The main purpose of phase I clinical trials is to study the safety of new drugs. Of course, we will also conduct drug efficacy trials. Throughout the history of clinical medicine, it has been thoroughly tested in phase I clinical trials of new drugs. It is very rare for a cured patient or a patient whose condition is greatly relieved. Even if you take the highest dose of the new drug, it is difficult to achieve the effect you desire. Unless a miracle occurs.”
“Miracle… miracle…” Ou Ye whispered, she remembered a line, if you don’t have a dream, what is the difference with salted fish.