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Chapter 1138 Introduction



Chapter 1138 Introduction

Xiao Linfeng sat in his office with a serious expression.

"President, the news has been confirmed." His secretary Matsutoshi whispered to Kobayashi Feng, "The outbreak in South Korea is serious, and the activities of the church are too frequent, and the virus may spread faster than everyone else. expected."

Xiao Linfeng is a very successful businessman. As the leader of Japan's largest pharmaceutical company, he must have a sharper sense of smell and long-term vision than everyone else.After receiving Sun Lien's warning as early as a week ago, Takeda Pharmaceutical's research department was almost entirely devoted to the development of therapeutic drugs for the new coronavirus.

The previously purchased Shire Pharmaceuticals suddenly played a huge role at this time. Shire Pharmaceuticals has two important product pipelines, one is the production and development department for rare disease therapies, and the other is the research and development of plasma products. department.

After the acquisition of Shire Pharmaceuticals, the research and development department of plasma products was mentioned by Takeda Pharmaceuticals as a highly valued level.The research projects in this department are mainly aimed at the direction of immunology.The immunization programs are divided into three categories - plasma immunization, vaccine immunization and tumor immunization.

According to feedback from Sun Lien and other researchers, all existing antiviral drugs are ineffective against the new coronavirus.In the most severely affected area in the world-Yunhe City, Xiangbei Province, China-the ultimate means for doctors to treat patients is convalescent plasma and ECMO.

Medical equipment has never been Takeda's strong point, and the research on immune plasma products was not an area they were good at before Takeda acquired Shire Pharmaceuticals.

But this time things are different.According to the various reports and feedback Xiao Linfeng has seen, in the current battle of Yunhe against the new coronavirus, Chinese medicine and biological agents have become the main means.Needless to say, the plasma of convalescents, and in the triple therapy pioneered by Sun Lien, the core tocilizumab, which prevents interleukin-6 from leading the inflammatory storm, is also a biological agent.

Shire's plasma products are running at full capacity.Their current main research direction is to extract plasma from recovered patients all over the world, and then try to produce large quantities of immunoglobulin and special-effect serum through bioengineering methods.

At present, Yunhe is the place with the largest number of recovered patients in the world, but almost all the plasma of recovered patients here has to be put into clinical treatment.Even if some can be provided to relevant institutions, as a foreign pharmaceutical company, Takeda will not be able to obtain these precious plasma for research.

Therefore, Kobayashi and Takeda Pharmaceutical have been paying close attention to the new coronavirus epidemic in other regions.Especially those countries that have Takeda agencies and can also export human plasma.

Traditionally, Europe is the most important source of global blood exports.More than 79% of exported blood (including human and animal blood) came from Europe, followed by North America.

However, the current epidemic is still mainly concentrated in Asia, and neither Takeda Pharmaceutical nor Shire Pharmaceutical has a license to carry out commercial pulp extraction in China.This also means that they can only turn their attention to other areas where the epidemic has already occurred.

Shire Pharmaceuticals currently has its own pulp collection center station in Italy, while Takeda Pharmaceuticals is actively laying pulp collection stations in Japan.

But Kobayashi was not satisfied. In order to meet the purpose of researching, producing, and operating specific therapies based on the new coronavirus recovered patients, Takeda Pharmaceutical needed more plasma from recovered patients.

Takeda Pharmaceuticals is currently facing two choices-either to cooperate with other CSLs that already have a global plasma production line, or to seize the opportunity by itself, find the next outbreak point in advance and speed up the pace of construction.In any case, as long as they want to continue to advance the project, they must obtain a large amount of plasma from convalescents as soon as possible.

As the helm of Takeda Pharmaceutical, Kobayashi Feng did not intend to take a big gamble - betting on the big luck is a move to die and survive when he can only choose one of the two.And Xiao Linfeng believes that it is enough for a company to gamble once in 50 years.It is really not worthwhile to gamble again in this kind of place.

As an excellent businessman, Xiao Linfeng certainly needs both.

"Notify Cui Dongjian and ask him to settle the matter of the pulp extraction station immediately." After listening to the report of Matsumoto's blog, Kobayashi Feng said decisively, "Let the agency immediately inject capital into the Korean branch, and first inject capital according to the scale of 500 billion yen. I only have one request, let Cui Dongjian give me all the money to go to the pulp extraction station within three months."

Hitoshi Matsushita touched his hair dyed blond and hesitated, "But now there are more than 800 cases of infection in South Korea, and 500 billion yen is all used to invest in pulp extraction stations... Is this too much?"

"The churches in South Korea are much more powerful than the churches in China." Xiao Linfeng said with a sneer, "Their trick to catch the believers is to hold mass and gatherings non-stop, so that these brainwashed people can continue to brainwash each other to deepen their impressions. To stop the spread of the virus, you must stop gatherings, but if you stop gatherings, a large number of believers will wake up and quit the church..." He looked at Matsumoto Otoshi and said, "Once these people quit the church, then those of them To whom can you sell the multimillion-dollar jug ​​that 'surely makes you happy'?"

"So, before their gatherings are forcibly terminated by Seoul, not only will the church not stop gatherings, but they may hold more frequent gatherings. On the one hand, doing so can strengthen the stickiness of believers, on the other hand... it can also take advantage of the opportunity Squeeze another wave of money." Matsumoto nodded, then scratched his head with his strong arms, "So, the number of confirmed patients will continue to rise."

"Residents in South Korea are fanatical about the church to a disturbing degree." Feng Xiaolin sneered twice and said, "As a country with an electoral system, the Blue House has the ability to offend a large number of specific groups of citizens. Natural fear. After all, politicians don't want to lose votes!"

"But South Korea went through MERS after all. As one of the victims of the coronavirus, they should still maintain a high level of vigilance." Matsuhito said in a low voice, "The question now is how much they remember."

"The situation in South Korea will only be more serious than Yunhe." Xiao Linfeng shook his head indifferently, he was very confident in his judgment, "Although the current president is hostile to the big chaebol,...he wants to follow suit Yunhe's measures are just a dream. It is impossible for chaebols to allow workers not to come to work, and it is impossible for investors who hold chaebol stocks to tolerate it. It is impossible for day-end workers who work for chaebols to accept it - just based on this , it is impossible for Blue House to emulate Yunhe."

As if he felt that what he said was not clear enough, Xiao Linfeng stood up from his seat, walked slowly to the window, looked at the night view of Tokyo Bridge outside the window and smiled, "To be honest, I originally thought that apart from Yunhe, the most The first outbreak will definitely be Yokohama."

A total of 691 confirmed cases have been reported among the passengers of the Gem Ji cruise ship.In addition, the Ministry of Health, Labor and Welfare has not been able to grasp the transmission route, and there are more than 140 cases of domestic infection.However, the spread of the novel coronavirus within Japan appears to be... quite different from its spread in other countries around the world, not even on the Majestic Princess.There are rumors from the outside world that this is all because the Japanese pay too much attention to personal space and have nothing to do with other people.

But Xiao Linfeng knew that this was bullshit.

Just look at the crowded trains on the Tokaido Line—it's the perfect hotbed for superspreading events.

The number of patients diagnosed with pneumonia caused by the new coronavirus in Japan has not risen rapidly. According to Kobayashi, there is only one reason.

Testing capacity across Japan is too limited.

As the capital, Tokyo's daily PCR testing capacity is 125, while among the 47 prefectures across the country, Kanagawa Prefecture, which has the strongest testing capacity, can test 190 samples per day.The national testing capacity combined can carry out a total of 2724 PCR tests per day.In other words, the PCR testing capacity of Japan is only about double that of Yunhe in early February.

Twice the testing capacity, but ten times the population.Such a disparity is already desperate enough, and what is even more frustrating is that under Japan’s loose healthcare system, even statistical data has become a desperate project—PCR test results reported to superiors in various places, Reports were made orally by fax or telephone.

This is also a key reason why Takeda Pharmaceutical is determined to invest in specific therapies.The epidemic data in Japan is completely a mystery. No one knows how many people have been infected with the virus among the 47 million people in the 700 prefectures.

The Cabinet has no capacity, no determination, no motivation to figure out what is going on.They are completely pretending to be deaf and dumb, and they don't intend to care at all.It seems that this disease has a high degree of discipline and organization, and it will only wreak havoc within China and not elsewhere.

It is only natural that the Cabinet is unreliable.Thinking of this, Xiao Linfeng sighed.For the safety of 700 million citizens, for the safety of Takeda Pharmaceutical's [-] employees in Japan and their families, he had to find a way.

"How's the connection with Johnson & Johnson and Modena?" He turned to Matsumoto and asked, "Have they agreed to the cooperation request?"

"Both Johnson & Johnson and Moderna are more positive about cooperation. But what they want more is to enter China for sales through our sales system and other channels." Matsumoto said helplessly, "As for the transfer of technology and production in Japan... …they haven’t given a definite answer on either of those two yet.”

"Johnson & Johnson is an established manufacturer, and they definitely want to keep all the profits in their own hands." Xiao Linfeng said after pondering for a while, "It is unlikely to cooperate with them. But the situation of Moderna is different—— — They have been established for four years, and they have not yet officially put a product on the market. There is no ready-made sales channel, and they lack experience in mass production... They need our help more than Johnson & Johnson.”

"Do you need to continue to increase the quotation to them?" Matsumoto asked, "Our current quotation still has at least 45% profit margin."

"If the quotation is too high, they will have concerns." Xiao Linfeng shook his head. He is too familiar with the greedy but timid habits of these European and American companies. "Tell them, we can pay in advance. Before the first phase of clinical trials begins , we can prepay a 1000% deposit for 30 million doses of vaccines. But the prerequisite is..."

"We must cooperate with us in production in Japan, and give Takeda the sales authority in Asia." Matsumoto nodded and said, "Such an excellent product.
It is impossible for Modena to refuse such a thick condition. "

"If they still plan to continue to procrastinate, then add another one." Xiao Linfeng tapped the table lightly, "We can send a technical team and a management team to assist them in establishing a large-scale production line in the United States and help them establish corresponding management systems. team."

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After learning about Bernard's experience, Bruen was shocked for a moment, and then said helplessly to his fellow countryman, "In the future, if you can't answer the calls from the United States, don't answer them."

"I definitely won't pick it up again." After receiving Sun Li'en's comfort, Bernard's spirit improved a lot.He came to Bruen, in fact, he wanted to remind his "citizen", "These reporters can do anything, Dr. Bruen, you also need to be careful-they can definitely get you too phone."

"They, call me?" Bruen froze for a moment, then overjoyed, "That would be great!"

As a member of the Communist Party, people like Brunn will be directly regarded as air by the American media.After all, in the eyes of Americans, the Communist Party members are all devils crawling out of hell.There is no law stipulating that communism is illegal in the United States, which has already made many Americans puzzled.Where else can a Communist Party be tolerated talking nonsense on American television?
As a member of the Communist Party, Bruen’s biggest dream is to appear on the mainstream media in the United States, and then prove a truth to the Americans watching TV-the Communist Party members are not devils, they love this country just like all other Americans , but also love their compatriots.

"Don't think too much." Bernard sighed and said, "They won't give you a chance to be on the live broadcast. After listening to a sentence you said, the content they reported will also use 26 Apart from the letters, there will no longer be any connection with what you originally said."

"That would be even better." Bruen chuckled, "After other Americans find out that the media they trust is actually interviewing a Communist Party, and has tampered with every word the Communist Party utters—do you think it will Is it me, the American Communist Party living in China, who is unlucky, or is it the media with dozens of lies mixed in one sentence?"

"You are a Communist Party?" Bernard looked surprised, but he quickly accepted the fact.After all, almost all the people he comes into contact with day and night are Communist Party members.He knew exactly what kind of people these party members were.

"I think you also have potential." Bruen chuckled, patted Bernard on the shoulder and asked, "Are you interested in joining us? I can be your party introduction."

(End of this chapter)


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