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Chapter 1132 Warning
Chapter 1132 Warning
After negotiating for a long time, Sun Lien finally reached an agreement with the Huangshan Medical Team to support 25 boxes of adult diapers, send 500 bottles of Coke, and [-] bottles of body lotion.
These materials were all obtained by Han Wenping, but Lao Han was more generous than Sun Lien - he lay on the bed and waved his hand, "Give them two hundred extra bottles of Coke!"
For doctors, things like cola are usually a tonic.It's not like the adult diapers that must be worn in protective clothing, or the pads and sanitary napkins that female medical staff must have during their menstrual period, and it's not like it is for doctors to disinfect multiple times a day, resulting in slightly dry or even cracked hands. Moisturizing body lotion.
But Coke is different.It is difficult for doctors to enjoy any particularly good "care" in their daily work, but they can make doctors deeply feel that they are still in "life".
People who work overtime all day long, even when they sleep at night, feel nervous.This is the most important point that Sun Lien has learned in the past month-when the mind is tense, the physical rest will inevitably be affected.
Doctors are usually very busy with their work, and the fatigue accumulated over a long period of time does exist.Regardless of whether the doctor himself can perceive such fatigue, the impact is always there.
But when Yunhe was fighting the epidemic, this impact, which was not very obvious at first, and might even be ignored, was suddenly multiplied.Especially the first batch of medical teams to support Yunhe showed the most obvious performance. More than half of the medical staff suffered from sleep disorders.
Sleep disorders will greatly affect the future work performance of medical staff and increase the risk of infection for everyone.For one thing, fatigue itself weakens immune function.On the other hand, people in a state of fatigue are not very clear in their minds, and it is difficult to concentrate for a long time and highly.
The effects of drowsy driving are not even that different from those of drunk driving.This shows how huge the impact of fatigue on people is.
In order to solve the sleep disorder, Sun Lien and the leadership of the medical team thought of countless ways.From sleeping pills to psychotherapy, and then chicken soup and rice, adjust the schedule.All kinds of methods were used, but what people didn't expect was that what really played a huge role was the batch of Coke that Director Han Wenping managed to get later.
On the third day after the unlimited supply of chicken soup and rice, Director Han began to serve Coke to everyone.In the beginning, it was only possible to share a bottle of Coke between two people every day.But after that, everyone can basically have a bottle of Coke to drink every day.
The supply of Coke made everyone feel that it was a novelty at first, but then Sun Lien was surprised to find that there were fewer and fewer doctors and nurses with "lack of sleep" on their heads.
The act of drinking Coke itself does not make people who already have sleep disorders feel better.But there is Coke to drink, but it can cheer up countless doctors and nurses who are already exhausted.From this point of view, Coke and Director Han contributed greatly.
Now, the medical team of Huangshan has also entered the battlefield, so preparing some good things for these colleagues who came from afar is the greatest kindness of the comrades who arrived on the battlefield in advance.
Comrades, are you here?This is the best thing we think is the most useful, and we give it all to you—be sure to work hard!
That's what these Cokes stand for.
·
·
·
Sun Li'en's logistics support work is actually not complicated, and he still has time to prepare for other tasks.
Like a phone call from an editor at New England Magazine.
According to what was written in the paper introducing triple therapy, the corresponding author should actually be Dr. Pascal in Ningyuan.But the triple therapy works really well, and there are a lot of special attention points in the treatment process-the New England editors have a keen interest in these special attention issues, but Dr. Pascale was not directly involved In clinical treatment, he could not give a qualified answer to these questions.
So, the editor of the New England Magazine decided to call Sun Lien, the first author of the article.Speaking of which, Sun Lien has published so many articles in New England, but they haven't contacted Sun Lien directly yet.
Sun Li'en learned the news this morning, but the logistical support left him with little time to prepare in advance.It can only be said that fortunately, this whole set of treatment plan was thought up by himself, and it has been widely applied in practice.Otherwise, he might really be stuttering and unable to answer the question.
"Doctor Sun, are you safe now?" After getting through the phone, the editor of the editorial department first asked about Sun Lien's situation, "How is Yunhe's situation now?"
"I'm in the hotel now, and Yunhe's situation has greatly improved compared to before." Sun Li'en replied honestly, "The number of new confirmed cases is now one-third of what it was before, and there are more cases every day. Hundreds of thousands of patients confirmed recovered and discharged - we are not far from victory."
The editor on the other end of the phone suddenly asked, "If you don't care about the propaganda, what do you think of Yunhe's situation?"
"Propaganda caliber?" Sun Lien asked subconsciously, and then frowned, "You mean, let me not mention the data published in the news, but only look at my intuitive feelings?"
"Yes." The New England editor said very sincerely, "China's data looks a bit too good, which makes many people feel that the new coronavirus is not terrible. But I hope to hear from the front-line doctors your intuition."
"There is nothing wrong with our data." Sun Lien felt a little angry in his heart, but he still tried to suppress his anger and said, "All the data of infected, recovered, and dead patients you have seen are real and reliable data. It can be quickly controlled. Such an infectious disease is due to our support with the strongest means, the most resolute actions, and the power of almost the entire country. With the support of national power, we have achieved this achievement with difficulty."
"You also feel that the number of patients has decreased in your clinical work?" The editor in New England seemed to have noticed Sun Lien's displeasure in his tone, and he decided to find a way to ask his question, "Please forgive my inappropriate wording, after all According to the reports of many international media, Yunhe's epidemic situation seems to be far less ... optimistic than that reported by the relevant Chinese authorities."
"Mr. Editor, you are the editor of a top medical journal with a long history." Sun Li'en was completely angry, and he asked quickly, "The reputation of "New England" has always been very good. The quality of the submission. I believe the scientific literacy of the editors also played a crucial role. But what you are doing now is simply unbelievable-do you think that those who even virus, coronavirus and Is the data provided by the so-called 'journalists' who don't know the difference between influenza viruses reliable?"
The more Sun Lien talked, the more angry he became. Of course, this is also human nature.No matter who it is, I and all my colleagues have worked hard for more than a month, and the situation has finally improved, but in the end, I will be smeared by those idiots who have never been to Yunhe. Anyone who is an individual will be furious .
"As an editor of a scientific journal, as a scientific research worker with a relevant degree, your behavior shocked me!" Sun Lien said angrily, "If you decide to believe those so-called reporters who have never been to Yunhe If the report sitting in the office and typing on the computer is credible, then I will think that the New England editorial department has lost the ability to discern real data, and will withdraw all upcoming and published articles in the New England Journal All articles!"
Sun Lien was extremely angry, and the "threat" he made was also very intense and serious.
Scientists from any country rarely voluntarily withdraw papers that have been published without any problems.Such behavior is almost innocuous to the journal and the editorial department, but it is a huge blow to the researchers themselves.
In previous bans, retracted papers were often withdrawn only because serious academic integrity issues were discovered, or serious and fundamental errors in the paper itself.
At least in the past, there has never been a scientist who voluntarily retracted a manuscript because he questioned the scientific literacy of the journal editorial department.When this kind of thing happened to New England, it seemed even more outrageous and incredible.
Lien Sun has published two articles in New England, and the study on the mechanism of AQP4 aquaporin deficiency syndrome published in Nature, and the treatment plan for AQP4 aquaporin deficiency published in Cell, are enough to make He became an important player who could not be ignored by the international medical and research community.When such a rising star withdraws in anger, the damage to New England's reputation is bound to be severe.
The editor on the other end of the phone was taken aback by Sun Lien's actions.To be honest, it is impossible to be so questioned by a young researcher without getting angry.But luckily this editor... he is a serious scientific researcher indeed.Ten seconds later, he readjusted his emotions.
"Let's not mention this issue for the time being. I think the WHO expert group will have a more credible statement and preliminary findings in two days." The editor coughed lightly, "Please understand that what we can obtain from the outside world The sources of news related to Yunhe are relatively single, and these single sources are indeed difficult to be used as direct credible evidence."
"I hope you can understand that if you question my article for scientific reasons, then I personally can accept it and will answer and explain it without reservation." Sun Li'en also calmed down a little and said, "But If you want to question my credibility, and the author has never been to Yunhe’s news reports, then I can only suspect that New England can no longer afford a scientific and objective book. status as a medical journal.”
·
·
·
Arguing with the editor before starting the text, Sun Lien really did not expect this kind of thing.But the good thing is that after threatening the other party, the editor obviously became more sober.
His main concern is the comparison between the mortality rate of the control group before triple therapy and the mortality rate after triple therapy.From this editor's perspective, there may be problems with the data for both groups.
"There is indeed a problem." Sun Li'en replied very sincerely, "The control group I use here is the Yunhe City Infectious Disease Hospital... who died before the triple therapy was used, and whose age was similar to that of the triple therapy receiving group. This data In fact, it must be high - if it is compared in areas other than Yunhe, the fatality rate of patients infected with new coronavirus pneumonia is much lower."
The case fatality rate of confirmed cases announced by Yunhe City around the 4th was about 4.9%, while the case fatality rate of confirmed cases in provinces other than Xiangbei Province was only 0.16%.The case fatality rate of confirmed patients in Yunhe City is more than 2.1 times that of other areas outside Xiangbei Province.The national average case fatality rate of confirmed cases is about [-]%.
"The patients who received the triple therapy were all severe or critically ill. This enrollment selection will also reduce the effectiveness of the triple therapy. However, considering that the mortality rate of the comparison data is higher than the actual situation, I think the situation of the treatment group and the control group It is still comparable." Sun Lien replied, "In fact, the effectiveness of the treatment group may be affected a little bit more."
The key to triple therapy is to stop the cell storm, and this "stop" is very specific and well-known.Since it is to be prevented, the patients should not be at the peak of "explosion" in the first place.In patients undergoing a severe cell storm, many inflammatory substances work together, and in this case, the use of tocilizumab can only block the action of interleukin-6.It will be much less effective than when used before and early in the outbreak.
The editor asked cautiously, "I can understand that the effect of triple therapy on these patients may be limited, but... Yunhe has a higher mortality rate than other regions. What is the reason?"
"Because medical resources are limited." Sun Lien sighed, "Medical resources are exhausted, which is the most serious challenge Yunhe has encountered before. When we cannot diagnose and accept all patients, the number of infected people will rapidly increase. And patients are more likely to change from mild to severe and critical." He paused, "The relevant diagnosis and treatment plans are all public, if you are interested in this topic, you may consider going to our trial Let’s take a look at the treatment plan.”
The editor thought about it, and then asked one last question.
"Your experiment that proved the effectiveness of the triple therapy clearly has room for further improvement. Of course, the current paper can be published, but don't you think it would be better to continue to improve the experiment and obtain more accurate data and conclusions?"
"Of course I don't care personally. But Mr. Editor, I am more worried about other countries in the world." Sun Lien shook his head, "In order to stop the spread, the measures we have taken are so tough, and the power invested is so huge Even so, we still lost the lives of many compatriots. Mr. Editor, this infectious disease is more dangerous than you think—don’t underestimate this disease just because we have achieved good results in Yunhe. After running out of medical treatment Before and after resources, it behaves like two completely different pathogens. And the speed at which it consumes all medical resources is much faster than you can imagine the limit."
(End of this chapter)
After negotiating for a long time, Sun Lien finally reached an agreement with the Huangshan Medical Team to support 25 boxes of adult diapers, send 500 bottles of Coke, and [-] bottles of body lotion.
These materials were all obtained by Han Wenping, but Lao Han was more generous than Sun Lien - he lay on the bed and waved his hand, "Give them two hundred extra bottles of Coke!"
For doctors, things like cola are usually a tonic.It's not like the adult diapers that must be worn in protective clothing, or the pads and sanitary napkins that female medical staff must have during their menstrual period, and it's not like it is for doctors to disinfect multiple times a day, resulting in slightly dry or even cracked hands. Moisturizing body lotion.
But Coke is different.It is difficult for doctors to enjoy any particularly good "care" in their daily work, but they can make doctors deeply feel that they are still in "life".
People who work overtime all day long, even when they sleep at night, feel nervous.This is the most important point that Sun Lien has learned in the past month-when the mind is tense, the physical rest will inevitably be affected.
Doctors are usually very busy with their work, and the fatigue accumulated over a long period of time does exist.Regardless of whether the doctor himself can perceive such fatigue, the impact is always there.
But when Yunhe was fighting the epidemic, this impact, which was not very obvious at first, and might even be ignored, was suddenly multiplied.Especially the first batch of medical teams to support Yunhe showed the most obvious performance. More than half of the medical staff suffered from sleep disorders.
Sleep disorders will greatly affect the future work performance of medical staff and increase the risk of infection for everyone.For one thing, fatigue itself weakens immune function.On the other hand, people in a state of fatigue are not very clear in their minds, and it is difficult to concentrate for a long time and highly.
The effects of drowsy driving are not even that different from those of drunk driving.This shows how huge the impact of fatigue on people is.
In order to solve the sleep disorder, Sun Lien and the leadership of the medical team thought of countless ways.From sleeping pills to psychotherapy, and then chicken soup and rice, adjust the schedule.All kinds of methods were used, but what people didn't expect was that what really played a huge role was the batch of Coke that Director Han Wenping managed to get later.
On the third day after the unlimited supply of chicken soup and rice, Director Han began to serve Coke to everyone.In the beginning, it was only possible to share a bottle of Coke between two people every day.But after that, everyone can basically have a bottle of Coke to drink every day.
The supply of Coke made everyone feel that it was a novelty at first, but then Sun Lien was surprised to find that there were fewer and fewer doctors and nurses with "lack of sleep" on their heads.
The act of drinking Coke itself does not make people who already have sleep disorders feel better.But there is Coke to drink, but it can cheer up countless doctors and nurses who are already exhausted.From this point of view, Coke and Director Han contributed greatly.
Now, the medical team of Huangshan has also entered the battlefield, so preparing some good things for these colleagues who came from afar is the greatest kindness of the comrades who arrived on the battlefield in advance.
Comrades, are you here?This is the best thing we think is the most useful, and we give it all to you—be sure to work hard!
That's what these Cokes stand for.
·
·
·
Sun Li'en's logistics support work is actually not complicated, and he still has time to prepare for other tasks.
Like a phone call from an editor at New England Magazine.
According to what was written in the paper introducing triple therapy, the corresponding author should actually be Dr. Pascal in Ningyuan.But the triple therapy works really well, and there are a lot of special attention points in the treatment process-the New England editors have a keen interest in these special attention issues, but Dr. Pascale was not directly involved In clinical treatment, he could not give a qualified answer to these questions.
So, the editor of the New England Magazine decided to call Sun Lien, the first author of the article.Speaking of which, Sun Lien has published so many articles in New England, but they haven't contacted Sun Lien directly yet.
Sun Li'en learned the news this morning, but the logistical support left him with little time to prepare in advance.It can only be said that fortunately, this whole set of treatment plan was thought up by himself, and it has been widely applied in practice.Otherwise, he might really be stuttering and unable to answer the question.
"Doctor Sun, are you safe now?" After getting through the phone, the editor of the editorial department first asked about Sun Lien's situation, "How is Yunhe's situation now?"
"I'm in the hotel now, and Yunhe's situation has greatly improved compared to before." Sun Li'en replied honestly, "The number of new confirmed cases is now one-third of what it was before, and there are more cases every day. Hundreds of thousands of patients confirmed recovered and discharged - we are not far from victory."
The editor on the other end of the phone suddenly asked, "If you don't care about the propaganda, what do you think of Yunhe's situation?"
"Propaganda caliber?" Sun Lien asked subconsciously, and then frowned, "You mean, let me not mention the data published in the news, but only look at my intuitive feelings?"
"Yes." The New England editor said very sincerely, "China's data looks a bit too good, which makes many people feel that the new coronavirus is not terrible. But I hope to hear from the front-line doctors your intuition."
"There is nothing wrong with our data." Sun Lien felt a little angry in his heart, but he still tried to suppress his anger and said, "All the data of infected, recovered, and dead patients you have seen are real and reliable data. It can be quickly controlled. Such an infectious disease is due to our support with the strongest means, the most resolute actions, and the power of almost the entire country. With the support of national power, we have achieved this achievement with difficulty."
"You also feel that the number of patients has decreased in your clinical work?" The editor in New England seemed to have noticed Sun Lien's displeasure in his tone, and he decided to find a way to ask his question, "Please forgive my inappropriate wording, after all According to the reports of many international media, Yunhe's epidemic situation seems to be far less ... optimistic than that reported by the relevant Chinese authorities."
"Mr. Editor, you are the editor of a top medical journal with a long history." Sun Li'en was completely angry, and he asked quickly, "The reputation of "New England" has always been very good. The quality of the submission. I believe the scientific literacy of the editors also played a crucial role. But what you are doing now is simply unbelievable-do you think that those who even virus, coronavirus and Is the data provided by the so-called 'journalists' who don't know the difference between influenza viruses reliable?"
The more Sun Lien talked, the more angry he became. Of course, this is also human nature.No matter who it is, I and all my colleagues have worked hard for more than a month, and the situation has finally improved, but in the end, I will be smeared by those idiots who have never been to Yunhe. Anyone who is an individual will be furious .
"As an editor of a scientific journal, as a scientific research worker with a relevant degree, your behavior shocked me!" Sun Lien said angrily, "If you decide to believe those so-called reporters who have never been to Yunhe If the report sitting in the office and typing on the computer is credible, then I will think that the New England editorial department has lost the ability to discern real data, and will withdraw all upcoming and published articles in the New England Journal All articles!"
Sun Lien was extremely angry, and the "threat" he made was also very intense and serious.
Scientists from any country rarely voluntarily withdraw papers that have been published without any problems.Such behavior is almost innocuous to the journal and the editorial department, but it is a huge blow to the researchers themselves.
In previous bans, retracted papers were often withdrawn only because serious academic integrity issues were discovered, or serious and fundamental errors in the paper itself.
At least in the past, there has never been a scientist who voluntarily retracted a manuscript because he questioned the scientific literacy of the journal editorial department.When this kind of thing happened to New England, it seemed even more outrageous and incredible.
Lien Sun has published two articles in New England, and the study on the mechanism of AQP4 aquaporin deficiency syndrome published in Nature, and the treatment plan for AQP4 aquaporin deficiency published in Cell, are enough to make He became an important player who could not be ignored by the international medical and research community.When such a rising star withdraws in anger, the damage to New England's reputation is bound to be severe.
The editor on the other end of the phone was taken aback by Sun Lien's actions.To be honest, it is impossible to be so questioned by a young researcher without getting angry.But luckily this editor... he is a serious scientific researcher indeed.Ten seconds later, he readjusted his emotions.
"Let's not mention this issue for the time being. I think the WHO expert group will have a more credible statement and preliminary findings in two days." The editor coughed lightly, "Please understand that what we can obtain from the outside world The sources of news related to Yunhe are relatively single, and these single sources are indeed difficult to be used as direct credible evidence."
"I hope you can understand that if you question my article for scientific reasons, then I personally can accept it and will answer and explain it without reservation." Sun Li'en also calmed down a little and said, "But If you want to question my credibility, and the author has never been to Yunhe’s news reports, then I can only suspect that New England can no longer afford a scientific and objective book. status as a medical journal.”
·
·
·
Arguing with the editor before starting the text, Sun Lien really did not expect this kind of thing.But the good thing is that after threatening the other party, the editor obviously became more sober.
His main concern is the comparison between the mortality rate of the control group before triple therapy and the mortality rate after triple therapy.From this editor's perspective, there may be problems with the data for both groups.
"There is indeed a problem." Sun Li'en replied very sincerely, "The control group I use here is the Yunhe City Infectious Disease Hospital... who died before the triple therapy was used, and whose age was similar to that of the triple therapy receiving group. This data In fact, it must be high - if it is compared in areas other than Yunhe, the fatality rate of patients infected with new coronavirus pneumonia is much lower."
The case fatality rate of confirmed cases announced by Yunhe City around the 4th was about 4.9%, while the case fatality rate of confirmed cases in provinces other than Xiangbei Province was only 0.16%.The case fatality rate of confirmed patients in Yunhe City is more than 2.1 times that of other areas outside Xiangbei Province.The national average case fatality rate of confirmed cases is about [-]%.
"The patients who received the triple therapy were all severe or critically ill. This enrollment selection will also reduce the effectiveness of the triple therapy. However, considering that the mortality rate of the comparison data is higher than the actual situation, I think the situation of the treatment group and the control group It is still comparable." Sun Lien replied, "In fact, the effectiveness of the treatment group may be affected a little bit more."
The key to triple therapy is to stop the cell storm, and this "stop" is very specific and well-known.Since it is to be prevented, the patients should not be at the peak of "explosion" in the first place.In patients undergoing a severe cell storm, many inflammatory substances work together, and in this case, the use of tocilizumab can only block the action of interleukin-6.It will be much less effective than when used before and early in the outbreak.
The editor asked cautiously, "I can understand that the effect of triple therapy on these patients may be limited, but... Yunhe has a higher mortality rate than other regions. What is the reason?"
"Because medical resources are limited." Sun Lien sighed, "Medical resources are exhausted, which is the most serious challenge Yunhe has encountered before. When we cannot diagnose and accept all patients, the number of infected people will rapidly increase. And patients are more likely to change from mild to severe and critical." He paused, "The relevant diagnosis and treatment plans are all public, if you are interested in this topic, you may consider going to our trial Let’s take a look at the treatment plan.”
The editor thought about it, and then asked one last question.
"Your experiment that proved the effectiveness of the triple therapy clearly has room for further improvement. Of course, the current paper can be published, but don't you think it would be better to continue to improve the experiment and obtain more accurate data and conclusions?"
"Of course I don't care personally. But Mr. Editor, I am more worried about other countries in the world." Sun Lien shook his head, "In order to stop the spread, the measures we have taken are so tough, and the power invested is so huge Even so, we still lost the lives of many compatriots. Mr. Editor, this infectious disease is more dangerous than you think—don’t underestimate this disease just because we have achieved good results in Yunhe. After running out of medical treatment Before and after resources, it behaves like two completely different pathogens. And the speed at which it consumes all medical resources is much faster than you can imagine the limit."
(End of this chapter)
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